The aim of the project is to gather the researchers and clinicians specialized in cystic fibrosis to discuss in depth the critical issues connected with the management of the pathology in adult age. Thanks to the important goals reached in the last years and looking at the new perspectives for life management of patients with Cystic Fibrosis, we look forward that this meeting can become a traditional appointment, to support always new approaches, treatments, and frontiers for Cystic Fibrosis.